2012 Peru

The first Spaniards arrived in the city on 15 November 1533. Francisco Pizarro officially arrived in Cuzco on 23 March 1534, renaming it the "Very noble and great city of Cuzco". The many buildings constructed after the Spanish invasion have a mixture of Spanish influence with Inca indigenous architecture, including the Santa Clara and San Blas neighborhoods. The Spanish destroyed many Inca buildings, temples and palaces. They used the remaining walls as bases for the construction of a new city.
The city was retaken from the Spanish during the Siege of Cuzco of 1536 by Manco Inca Yupanqui, a leader of the Sapa Inca. Although the siege lasted ten months, it was ultimately unsuccessful. Manco's forces were able to reclaim the city for only a few days. Throughout the conflict and years of the Spanish colonization of the Americas many of Inca citizens and warriors succumbed to smallpox and died. (from Wikipedia)